盐酸普萘洛尔 分析标准品
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| 熔点: | 163-165° C |
| 包装规格: | 25mg in glass bottle |
| 溶解性: | 溶于水(50 mg/ml)、乙醇(10 mg/ml)、DMSO (<14.5 mg/ml)和甲醇。 |
| 产品描述: | 一种β1和β2肾上腺素受体抑制剂。Propranolol hydrochloride is a cationic amphiphillic molecule shown to block β1 and β2 adrenergic receptors with similar efficacy, without affecting α adrenergic receptors. Demonstrates high affinity for SR-1B (5-HT1B) receptors (Ki = 17nM), and milder affinity for SR-1D (5HT-1D) receptors (Ki = 10.2 μM). Propranolol hydrochloride also has been shown to inhibit the formation of phospholipase D-derived diacylglycerol (DAG) by inhibiting cytosolic phosphatidate phosphohydrolase; making propranolol a useful tool for investigating phospholipase D-, and phospholipase C-mediated DAG production. Propranolol hydrochloride is an inhibitor of AR. |
| 保存条件: | -20℃ |
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