2ˊ-脱氧次黄嘌呤核苷  分析标准品

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包装规格:20mg in glass bottle
溶解性:溶于DMSO(50mg/mL超声)
产品描述:能够抑制人癌细胞株的生长,并发现其与嘌呤核苷磷酸化酶 (PNP) 缺乏有关。2’-Deoxyinosine is the nucleoside form of hypoxanthine. It is a product of DNA damage that is formed from 2’-deoxyadenosine by adenosine deaminase or reactive nitrogen species. 2’-deoxyinosine enhances apoptosis induced by 5-fluorouracil in HT-29 and SW620 cancer cells. It also enhances 5-FU-induced tumor growth suppression in an SW620 mouse xenograft model when administered at a dose of 1.6 g/kg twice per day.
保存条件:-20℃