三氯苯达唑 分析标准品
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| 包装规格: | 100mg in glass bottle |
| 溶解性: | 溶于DMSO(100 mg/mL 超声) |
| 产品描述: | 为苯并咪唑,与微管蛋白结合,损害细胞内运输机制,且干扰蛋白质的合成。 Triclabendazole is an anthelmintic and fasciolicidal, binding to beta-tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and/or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and enzyme synthesis. These metabolic disturbances are associated with inhibition of motility, disruption of the surface as well as ultrastructure that includes inhibition of spermatogenesis and vitelline cells. |
| 保存条件: | 室温 |
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