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3-甲基-1-苯基-2-吡唑啉-5-酮  分析标准品

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熔点：126-128°C
包装规格：100mg 1g in glass bottle
溶解性：溶于水(3.3 g/L at 20° C）、 DMSO (~30 mg/ml)、甲醇、乙醇 (~15 mg/ml)和DMF (~50 mg/ml)
产品描述：一种通过JNK途径增强NGF蛋白水平的自由基清除剂。MCI-186, also known as 3-methyl-1-phenyl-2-pyrazolin-5-one, is a free radical scavenger that has been shown to contain protective properties towards murine brain ischemia. In vitro this compound has been reported to decrease cell death in murine models. Mechanistic studies suggest that MCI-186 enhances neuronal growth factor (NGF) protein levels which are essential for neuronal growth and survival. Furthermore, the enhancement of NGF expression in astrocytes has been thought to be done via the c-Jun N-terminal Kinase (JNK) pathway.
保存条件：室温

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