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包装规格:100mg in glass bottle
溶解性:溶于DMSO(50 mg/mL 超声)
产品描述:单环β-内酰胺抗生素,与青霉素结合蛋白3(PBP-3)有较高亲和力。Aztreonam is a monobactam antibiotic used primarily to treat infections caused by gram-negative bacteria. Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity. Aztreonam preferentially binds to and inactivates penicillin-binding protein-3 (PBP-3), which is involved in bacterial cell wall synthesis, thereby inhibiting bacterial cell wall integrity and leading to cell lysis and death. This agent differs from other beta-lactam antibiotics because it is resistant to beta-lactamase hydrolysis, and it is usually used to treat infections caused by gram-negative aerobic microorganisms.
保存条件:2-8°C