氨曲南 文献数量:1 分析标准品
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| 包装规格: | 100mg in glass bottle |
| 溶解性: | 溶于DMSO(50 mg/mL 超声) |
| 产品描述: | 单环β-内酰胺抗生素,与青霉素结合蛋白3(PBP-3)有较高亲和力。Aztreonam is a monobactam antibiotic used primarily to treat infections caused by gram-negative bacteria. Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity. Aztreonam preferentially binds to and inactivates penicillin-binding protein-3 (PBP-3), which is involved in bacterial cell wall synthesis, thereby inhibiting bacterial cell wall integrity and leading to cell lysis and death. This agent differs from other beta-lactam antibiotics because it is resistant to beta-lactamase hydrolysis, and it is usually used to treat infections caused by gram-negative aerobic microorganisms. |
| 保存条件: | 2-8°C |
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