阿昔洛韦 分析标准品
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| 包装规格: | 100mg in glass bottle |
| 溶解性: | 溶于DMSO(7mg/mL) |
| 产品描述: | 一种鸟苷类似物,作为抗代谢物。Acyclovir is an antiviral compound that can be used to induce apoptosis in cells transfected with herpes simplex virus thymidine kinase (HSV-TK). The compound may exert inhibitory effects through the alterations of the cell cycle in leukemia cells lines, such as p185BCR-ABL expressing OM9;22 cells, by synchronizing the G0/G1 phase. Formation of acycloguanosine triphosphate occurs through the phosphorylation of HSV-TK and can inhibit the viral DNA polymerase. Acyclovir also has the ability to inhibit the proliferation of the fibroblast cells, NIH 3T3, transformed with v-abl or bcr-abl. |
| 保存条件: | 2-8°C |
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