(+)-δ-生育酚  分析标准品

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包装规格:100mg 250mg in glass bottle
溶解性:溶于DMSO(125mg/mL超声)
产品描述:维生素 E 的一个异构体。D-δ-Tocopherol is a biologically active form of vitamin E, a lipid-soluble antioxidant that protects cellular membranes from oxidative damage. It reduces cumene hydroperoxide-induced lipid peroxidation in hepatocytes when used at a concentration of 20 µM but induces lipid peroxidation in hepatic microsomes at 100 µM. D-δ-Tocopherol decreases capillary formation of HMEC-1 blood endothelial cells. It also decreases the expression of VCAM in, and the invasiveness of, HMEC-1 cells. D-δ-Tocopherol reduces estrogen-induced increases in the expression of the estrogen-responsive genes encoding TFF/pS2, cathepsin D, PGR, CITED1, and SERPINA1 and the levels of 8-hydroxy-2’-deoxyguanosine (8-oxo-dG) and nitrotyrosine in MCF-7 breast cancer cells. Dietary administration of D-δ-Tocopherol reduces tumor growth in an estrogen-supplemented MCF-7 mouse xenograft model.
保存条件:-20°C