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鸦胆亭  ≥98%(HPLC),分析标准品

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包装规格：10mg in glass bottle
溶解性：溶于DMSO（100mg/mL超声）
产品描述：从痢鸦胆子中提取，对B16黑色素瘤，结肠癌38，L1210和白血病P388有抑制性。Bruceantin is a quassinoid originally isolated from B. antidysenterica that has diverse biological activities. It inhibits protein synthesis in HeLa cells, reticulocytes, and reticulocyte lysates (IC50s = 30, 40, and 1,600 nM, respectively). Bruceantin is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50s = 8 and 13 nM, respectively). It induces apoptosis in HL-60 leukemia and RPMI-8226 multiple myeloma cells (IC50s = 12.2 and 12.8 nM, respectively). Bruceantin (5 mg/kg) induces tumor regression in an RPMI-8226 mouse xenograft model.
保存条件：-20℃

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