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党参炔苷  ≥98%(HPLC),分析标准品

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包装规格：10mg in glass bottle
产品描述：基本信息 产品编号： L10334 产品名称： Lobetyolin CAS: 129277-38-9   储存条件 粉末 -20℃(避光) 四年 分子式： C20H28O8 溶于液体 -80℃(避光) 6个月 分子量： 396.43 -20℃(避光) 1个月 化学名：  (2R,3R,4S,5S,6R)-2-[(4E,12E)-1,7-dihydroxytetradeca-4,12-dien-8,10-diyn-6-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Solubility (25°C)：   体外:   DMSO   Ethanol   Water   体内(现配现用):   ＜1mg/ml表示微溶或不溶。 普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。   制备储备液   浓度   溶液体积 质量   1mg   5mg   10mg 1mM 2.5225mL 12.6126mL 25.2251mL 5mM 0.5045mL 2.5225mL 5.0450mL 10mM 0.2523mL 1.2613mL 2.5225mL   生物活性 产品描述 一种分离自Codonopsis pilosula的生物活性化合物。Lobetyolin具有抗炎，抗氧化和黄嘌呤氧化酶抑制活性。 靶点 Apoptosis;Xanthine Oxidase 体外研究 Lobetyolin is derived from Codonopsis pilosula and has antioxidative effect.MUC5AC gene expression induced by phorbol 12-myristate 13-acetate (PMA) from NCI-H292 cells is inhibited by pretreatment with Lobetyolin,lobetyol or methyl linoleate.Lobetyolin does not affect PMA-induced MUC5AC production from NCI-H292 cells.The amounts of mucin in the cells of Lobetyolin-treated cultures are 100±25%,487±33%,524±38%,411±24%,and 402±45% for control,10ng/mL of PMA alone,PMA plus Lobetyolin 1μM,PMA plus Lobetyolin 10μM,and PMA plus Lobetyolin 100μM,respectively.   推荐实验方法(仅供参考) 细胞实验:   After 24 hours of serum deprivation,cells are pretreated with Lobetyolin,lobetyol or methyl linoleate (1,10,and 100µM),for 30 minutes and then treated with phorbol 12-myristate 13-acetate (PMA;10ng/mL) for 24 hours in serum-free RPMI 1640.After 24 hours,the spent media are collected to measure the secretion of MUC5AC protein and cells are lysed with buffer solution containing 20mM Tris,0.5% NP-40,250mM NaCl,3mM EDTA,3mM EGTA,and protease inhibitor cocktail and collected to measure the production of MUC5AC protein (in 24-well culture plate).
保存条件：-20℃ 避光

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