1-BCP
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| 包装规格: | 5mg in glass bottle |
| 产品描述: | 一种中枢活性药物,调节AMPA受体的门控电流。1-BCP是一种可增强记忆的药物。1-BCP is a positive allosteric modulator of AMPA receptors. 1-BCP (1 mM) selectively increases the release of norepinephrine induced by AMPA, but not NMDA or kainic acid, in rat hippocampal slices. It increases the amplitude and duration of primed field excitatory postsynaptic potentials (EPSPs) in rat hippocampal slices (EC50s = 480 and 590 µM, respectively). 1-BCP enhances memory in two-odor discrimination and radial maze tests, as well as in the Morris water maze, in rats when administered at a dose of 120 mg/kg. |
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