3-CPs ≥95%
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| 包装规格: | 1g in glass bottle |
| 产品描述: | 基本信息 产品编号: C11713 产品名称: 3-CPs CAS: 20073-24-9 储存条件 粉末 -20℃ 四年 分子式: C14H10O5 溶于液体 分子量 258.23 化学名: 3-Carbethoxypsoralen; 3-Ethoxycarbonylpsoralen 生物活性 产品描述 可以干扰抗体介导的细菌杀伤的血清型荚膜多糖。 体外研究 3-CPs displays protective effect against UVB damage in all concentrations tested. About 50% inhibition of bacterial killing is observed when 12 ng of purified type 3 CPS is added to the OPKA. The addition of 30μL of mouse serum post-i.p. infection with WU2 (containing 0.4 to 0.7μg/mL released type 3 CPS) shows 26% to 52% inhibition of bacterial killing, comparable to what is observed when an equivalent amount of purified CPS is added 推荐实验方法(仅供参考) Kinase Assay To measure the inhibitory effect of releaseing type 3-CPs on bacteria killing, an OPKA is performed with the addition of culture supernatant or mouse serum obtained at 24 h following i.p. injection with 103 CFU of the S. pneumoniae WU2 strain. In each well, 10μL of diluted rabbit serum is mixed with 10μL of strain WU2 (1,000 CFU) and 10μL of culture supernatant or mouse serum for 30 min at room temperature before HL-60 cells and complement are added. The percent inhibition of bacterial killing is compared to that with the OPKA with the addition of ΔCPS WU2 culture supernatant or naive mouse serum containing no 3-CPs |
| 保存条件: | -20°C |
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