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Ropidoxuridine  ≥98%

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包装规格：5mg 25mg in glass bottle
产品描述：一种新型口服，卤化胸苷类似物，有希望用于人类肿瘤的增敏剂。Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of glioma. Preclinical studies have also demonstrated that Ropidoxuridine has dose responsive and synergistic effects when combined with radiation in human glioblastoma models. Ropidoxuridine has also shown reduced toxicity, with better tissue incorporation and improved anti-tumor activity when compared to IUdR in nonclinical models. Ropidoxuridine was in clinical trials in patients with colorectal, gastric, and pancreatic cancer, and other solid tumors.
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