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Clozic  ≥95%

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包装规格：1g in glass bottle
产品描述：基本信息 产品编号： C11721 产品名称： Clozic CAS: 22494-47-9   储存条件 粉末 -20℃ 四年     分子式： C17H17ClO3 溶于液体     分子量 304.77     化学名：  2-[[4-(4-chlorophenyl)phenyl]methoxy]-2-methylpropanoic acid   生物活性 产品描述 一种潜在的抗关节炎药物。 体外研究 Clozic is a potential anti-arthritic agent. Concentrations of Clozic greater than 50μM cause a dose-dependent decrease in the amount of matrix protein synthesized by RHMC cell cultures. Inhibition of RHMC cell culture growth by Clozic occurs in a dose-dependent manner. The anti-proliferative effect of Clozic on RHMC cell growth is reversible. Lactate dehydrogenase (LDH) levels in media taken from RHMC cell cultures exposed to 500μM Clozic for 3 days do not significantly differ from LDH levels in control cell culture media   推荐实验方法(仅供参考) Cell Assay Approximately 3×104 to 5×104 cells/mL medium are seeded into 24-well plates and incubated at 37°C in a humidified atmosphere of 95% air/5% CO2. Medium is replaced with fresh medium containing 20% foetal calf serum and methanol or Clozic under investigation. Cell numbers are determined in replicate wells on various days during culture growth
保存条件：-20°C

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