Ingliforib  ≥98%

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包装规格:5mg 10mg 50mg 100mg in glass bottle
产品简介:一种 glycogen phosphorylase 抑制剂,对肝脏、肌肉和大脑 glycogen phosphorylase 的 IC50 值分别为 52,352 和 150 nM,具有心脏保护的作用。 Ingliforib, also known as CP-368296, is a novel glycogen phosphorylase inhibitor. Ingliforib has antihyperglycemic and cardioprotective properties. Ingliforib inhibits glycogen phosphorylase, the rate-limiting enzyme in glycogenolysis, thereby preventing the release of glucose-1 phosphate from a glycogen molecule in liver. This agent also inhibits glycogen phosphorylase in cardiac muscle and may protect the heart from myocardial ischemic injury by preserving glycogen content and improving glycolytic-oxidative coupling.
溶解性:溶于DMSO(130mg/mL超声)
产品描述:一种 glycogen phosphorylase 抑制剂,对肝脏、肌肉和大脑 glycogen phosphorylase 的 IC50 值分别为 52,352 和 150 nM,具有心脏保护的作用。Ingliforib, also known as CP-368296, is a novel glycogen phosphorylase inhibitor. Ingliforib has antihyperglycemic and cardioprotective properties. Ingliforib inhibits glycogen phosphorylase, the rate-limiting enzyme in glycogenolysis, thereby preventing the release of glucose-1 phosphate from a glycogen molecule in liver. This agent also inhibits glycogen phosphorylase in cardiac muscle and may protect the heart from myocardial ischemic injury by preserving glycogen content and improving glycolytic-oxidative coupling.
保存条件:-20℃