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Ertiprotafib  

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包装规格：1mg in glass bottle
产品描述：一种PTP1B，IKK-β的抑制剂，其IC50值分别是1.6μM，400nM，同时也是PPARα/PPARβ的激动剂，其EC50值为~1μM。Ertiprotafib, also known as PTP-112, is a Protein Tyrosine Phosphatase 1B Inhibitor (PTP1B inhibitor). Ertiprotafib normalized the plasma glucose and insulin levels in diabetic animal models, and progressed to a phase II clinical trial. Ertiprotafib is potentially useful for the treatment of Non-Insulin Dependent Diabetes. Ertiprotafib improves glycemic control and lowers lipids via multiple mechanisms. Ertiprotafib is also a potent inhibitor of IkappaB kinase beta (IKK-beta), with an IC(50) of 400nM.
保存条件：-20℃

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