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PF-05085727  ≥98%

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包装规格：5mg 10mg 25mg 50m gin glass bottle
溶解性：溶于DMSO(2mg/mL)
产品描述：一种强效的 cGMP 依赖性的 PDE2A (IC50=2 nM) 选择性和具有脑通透性的抑制剂。PF-05085727 is a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor. PF-05085727 demonstrated in vivo activity as evidenced by biochemical increases in brain cGMP accumulation in rodent brain regions expressing highest levels of PDE2A enzyme. Additionally, behavioral and electrophysiological changes due to two different NMDA antagonists were reversed at exposures where PF-05085727would selectively inhibit PDE2A without activity at any other target.
保存条件：-20℃

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