NSC624206  

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包装规格:1mg in glass bottle
产品描述:一种泛素 E1 (UBA1) 抑制剂,其 IC50 值为 ~9 μM。NSC624206 特异性地阻断泛素-硫代酯的形成,但对泛素腺化无影响。NSC-624206 hydrochloride is an inhibitor of ubiquitin-activating enzyme (E1) that specifically blocks ubiquitin-thioester formation but has no effect on ubiquitin adenylation. Through this action, NSC-624206 prevents the ubiquitination and degradation of the tumor suppressor protein p27 in vitro.
保存条件:-20℃