K-604 dihydrochloride  ≥98%

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包装规格:5mg 10mg 25mg 100mg in glass bottle
溶解性:溶于DMSO(10mg/ml)
产品描述:一种有效的选择性酰基辅酶A:胆固醇酰基转移酶1(ACAT-1)抑制剂K-604 is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor. K-604 inhibits against acyl-coenzyme A (acyl-CoA):cholesterol O-acyltransferase-1 (ACAT1, SOAT1) activitiy in a selective (IC50 = 450 nM vs. 102.85 μ M against human ACAT1 and ACAT2, respectively) and acyl-CoA-competitive (Ki = 378 nM against oleoyl-coA) manner.
保存条件:-20℃