盐酸酚苄明  ≥98%

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包装规格:1g 5g 25g in glass bottle
溶解性:溶于DMSO(100mg/mL 超声)
产品描述:一种具有选择行的 α-adrenoceptor 和 calmodulin 的抑制剂,是一种常用的抗高血压药。 Phenoxybenzamine hydrochloride is an α-1 adrenergic receptor antagonist used to treat hypertension and as a peripheral vasodilator. Phenoxybenzamine reduced neuronal death in rat hippocampal slice cultures following exposure to oxygen glucose deprivation. Phenoxybenzamine treated TBI (traumatic brain injury) animals also showed a significant improvement in both learning and memory compared to saline treated controls. At 32 h post-TBI phenoxybenzamine treated animals had significantly lower expression of pro-inflammatory signaling proteins CCL2, IL1β, and MyD88, suggesting that phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after TBI.
保存条件:2-8℃