尾海兔素10 ≥98%
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{{item.title}}
| 包装规格: | 1mg 5mg 10mg 25mg in glass bottle |
| 产品简介: | 一种有效的从海洋软体动物Dolabela auricularia中分离出来的抗有丝分裂肽,抑制微管蛋白聚合。 |
| 溶解性: | 溶于DMSO(≥ 100 mg/mL) |
| 储备液保存: | 该产品在溶液状态不稳定,建议您现用现配,即刻使用。 |
| 靶点: | Auristatin |
| 体外研究: | Dolastatin 10 is a unique pentapeptide that isolated from the sea hare Dolabella auricularia. These in vitro data are quite comparable to those of Dolastatin 10 and Auristatin PE, each of which has GI50 values of 10−5-10−6 μg/mL (10−2-10−3 nM) against a similar minipanel of human cell lines. The antibody-drug conjugate (ADC) comprises the anti-CD30 monoclonal antibody cAC10 conjugated to the cytotoxic agent monomethyl auristatin E (MMAE), a synthetic analog of the tubulin polymerization inhibitor Dolastatin 10. |
| 保存条件: | -20℃ |
| 注意事项: | 1、为了您的安全和健康,请穿实验服并戴一次性手套操作。 2、以上信息仅做参考交流之用。 |
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