Mal-PEG4-acid  

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包装规格:100mg 250mg 500mg in glass bottle
产品描述:一种基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。Mal-PEG4-acid is a PEG derivative containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
保存条件:-20℃