Mal-PEG4-acid
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| 包装规格: | 100mg 250mg 500mg in glass bottle |
| 产品描述: | 一种基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。Mal-PEG4-acid is a PEG derivative containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
| 保存条件: | -20℃ |
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