硫酸巴龙霉素  分析标准品

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包装规格:100mg in glass bottle
产品简介:一种的广谱氨基糖苷类抗生素,具有杀螨杀菌作用,是新霉素衍生物。 Paromomycin sulfate is an aminoglycoside antimicrobial agent derived from Streptomyces sp. AG-P 1441. Paromomycin likely induced resistance as confirmed by the expression of pathogenesis-related genes: PR-1, β-1,3-glucanase, chitinase, PR-4, peroxidase, and PR-10, which enhanced plant defense against P. capsici in chili pepper.
溶解性:溶于DMSO(1 mg/mL超声,加热)
储备液保存:-80°C, 6 months; -20°C, 1 month。 (sealed storage, away from moisture)
体内实验:1、请依序添加每种溶剂: PBS Solubility: 100 mg/mL (140.11 mM); 澄清溶液; 超声助溶 注:建议现用现配,在短期内尽快用完。 <1mg/ml表示微溶或不溶。 普西唐提供的所有化合物浓度为内部测试所得,实际溶液度可能与公布值有所偏差,属于正常的批间细微差异现象。 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
靶点:Aminoglycoside;Amebae
体外研究:Paromomycin sulfate (500 μg/ml) reduces intracellular parasitic forms by 97.2% compared to control in Caco-2 cells and reduces the percentage of intracellular C. parvum forms by 99.5% in HCT-8 cells.
体内研究:Paromomycin sulfate (oral gavage; 50 mg/kg-200 mg/kg; once daily; for five consecutive days two weeks post infection) reduces the number of oocyst per gram of feces and intestine. It shows minimal focal inflammation in only 20% of the sections at 50 mg/kg from the intestines of mice infected with C. parvum and only 10% of focal inflammation at 200 mg/kg.
保存条件:-20°C
注意事项:1、为了您的安全和健康,请穿实验服并戴一次性手套操作。 2、以上信息仅做参考交流之用。