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TH-237A  ≥98%

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包装规格：5mg 10mg 50mg 100mg 200mg 500mg in glass bottle
溶解性：溶于Ethanol（100mg/mL 超声)
产品描述：一种神经保护剂，有很好的血脑屏障渗透性。TH-237A is a novel neuroprotective agent, which possess protective properties against β-amyloid (Aβ)-induced neurodegeneration associated with Alzheimer's disease. Exposure of neuronal cultures to Aβ peptide in the presence of 5 nM TH-237A resulted in a 50% increase in survival. Neuronal cultures treated with other toxic stimuli such as staurosporine, thapsigargin, paraquat and H2O2 showed significantly enhanced survival in the presence of TH-237A . Microtubule binding and tubulin assembly studies revealed differences compared to paclitaxel, but confirmed the interaction of TH-237A with microtubules.
保存条件：-20°C

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