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| 包装规格: | 1g in glass bottle |
| 产品描述: | 基本信息 产品编号: A12880 产品名称: Anitrazafen CAS: 63119-27-7 储存条件 粉末 -20℃ 四年 分子式: C18H17N3O2 溶于液体 分子量 307.35 化学名: 5,6-bis(4-methoxyphenyl)-3-methyl-1,2,4-triazine 生物活性 产品描述 一种局部有效的抗炎剂。 体内研究 Anitrazafen is a topically effective antiinflammatory agent. The disposition of 14C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25mg/kg of [3-14C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total 14C after subcutaneous administration of [3-14C]Anitrazafen in corn oil solution are about one half those found after oral administration 推荐实验方法(仅供参考) Animal Administration Male albino rats (200 to 250g) are fasted for 24 h before experiment. [3-14C]Anitrazafen (25mg/kg) is administered orally to twelve rats. At specific times after dosing, three animals are killed by decapitation and samples of blood and appropriate tissues are removed. Duplicate weighed samples of blood and each tissue are removed for 14C assay |
| 保存条件: | -20°C |
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