Volixibat  

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包装规格:1g in glass bottle
产品描述:一种高选择性、低吸收、竞争性的顶端钠依赖性胆汁酸转运体 (ASBT) 抑制剂。Volixibat 有潜力用于非酒精性脂肪性肝炎 (NASH) 的研究。Volixibat, also known as LUM-002, SHP-626, SAR-548304, is a medication under development as a possible treatment for nonalcoholic steatohepatitis (NASH), the most severe form of non-alcoholic fatty liver disease (NAFLD). No other pharmacotherapy yet exists for NASH, so there is interest in whether volixibat can prove to be both safe and effective. Volixibat is an IBAT inhibitor, meaning that it blocks the function of the IBAT protein (ileal bile acid transporter), which is also called SLC10A2 (solute carrier family 10 member 2) or ASBT (apical sodium–bile acid transporter).
保存条件:-20℃