K-7174 dihydrochloride ≥98%
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| 包装规格: | 5mg 10mg 50mg in glass bottle |
| 产品描述: | 细胞粘附抑制剂,能抑制VCAM-1的表达量。K-7174 is a novel orally active, potent proteasome inhibitor. K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib. K-7174 is also a GATA-specific inhibitor, which may have potential application in treating anemia of chronic disease. |
| 保存条件: | -20℃ |
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