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ISO-1  ≥98%

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包装规格：5mg 25mg 50mg in glass bottle
溶解性：溶于DMSO（50mg/mL超声）
产品描述：巨噬细胞移动抑制因子(MIF) 拮抗剂，IC50 值为 7 μM。ISO-1, also known as MIF Antagonist and ISO-1 and Macrophage Migration Inhibitory Factor, is a MIF inhibitor. ISO-1 has CAS#478336-92-4. MDK-6924 Protects Photoreceptors and Reduces Gliosis in Experimental Retinal Detachment. Systemic administration of the MIF inhibitor ISO-1 significantly blocked photoreceptor apoptosis, outer nuclear layer (ONL) thinning, and retinal gliosis. ISO-1 and MIF knockout (MIFKO) had greater accumulation of Müller glia pERK expression in the detached retina, suggesting that Müller survival pathways might underlie the neuroprotective response.
保存条件：-20℃

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