Lomitapide  98.88%

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包装规格:10mg 50mg in glass bottle
溶解性:溶于DMSO(20mg/mL)
产品描述:一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂, 体内试验的IC50值为8 nM。Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozygous familial hypercholesterolemia. Lomitapide is an orally active inhibitor of microsomal triglyceride transfer protein that is indicated as an adjunct to a low-fat diet and other lipid-lowering treatments, including LDL apheresis where available for the reduction of LDL-C, total cholesterol, apolipoprotein B, and non-high-density lipoprotein cholesterol in adult patients with HoFH.
保存条件:-20℃