Glimepiride  ≥98%

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包装规格:1g 5g 25g in glass bottle
溶解性:溶于DMSO(30mg/mL 超声)
产品描述:一种中长效的磺酰脲类抗糖尿病化合物,ED50为 182 μg/k。Glimepiride is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Glimepiride increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.
保存条件:室温