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Glyco-Obeticholic acid  

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包装规格：5mg in glass bottle
产品描述：牛磺酸的活性代谢物。ObeticholicAcid是一种口服生物可利用的法尼样X受体(FXR)激动剂。Glyco-obeticholic acid is an active metabolite of obeticholic acid, which is a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid. Glyco-obeticholic acid is formed from obeticholic acid by glycine conjugation in the liver but can be reconverted back to obeticholic acid by microorganism-mediated deconjugation in the ileum and colon. It has been used as a precursor in the synthesis of bile acid analogs as agonists of the farnesoid X receptor (FXR) and TGR5.
保存条件：-20℃

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