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SR9243  ≥98%

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包装规格：5mg 25mg 100mg in glass bottle
溶解性：溶于DMSO(10mg/ml)
产品描述：一种liver-X-receptor(LXR)的反向激动剂，能够诱导LXR-辅阻遏物相互作用。SR9243 is a potent and selective LXR inverse agonist. SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect. SR9243 induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes. In cancer cells, SR9243 significantly inhibited the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression. SR9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. Malignant cells exhibit aerobic glycolysis (the Warburg effect) and become dependent on de novo lipogenesis, which sustains rapid proliferation and resistance to cellular stress.
保存条件：-20℃

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