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包装规格:10mg 50mg 100mg in glass bottle
溶解性:溶于DMSO(≥25mg/mL )
产品描述:一种有效的选择性的组织蛋白酶抑制剂,IC50分别为0.2n和1n。Odanacatib, also nown as -0822, is an inhibitor of cathepsin with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin , which ay result in a reduction in bone resorption, iproveent of bone ineral density, and a reversal in osteoporotic changes. Cathepsin , a tissue-specific cysteine protease that catalyzes degradation of bone atrix proteins such as collagen I/II, elastin, and osteonectin plays an iportant role in osteoclast function and bone resorption. Chec for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
保存条件:-20℃