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Ulixertinib HCl 促销  ≥98%

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包装规格：5mg 25mg 50mg 100mg in glass bottle
产品简介：一种有效、可口服、高度选择性、ATP-竞争性、可逆、共价的ERK1/2抑制剂。 Ulixertinib is an inhibitors of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
溶解性：DMSO：100 mg/mL (212.86 mM; 超声助溶) Water：< 0.1 mg/mL (insoluble)
保存条件：室温

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