西达本胺 ≥98%(HPLC)
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| 包装规格: | 5mg 25mg 100mg in glass bottle |
| 溶解性: | 溶于DMSO(≥40mg/mL) |
| 产品描述: | 一种口服有效的HDAC1/2/3抑制剂。Chidamide is a n orally bioavailable benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10, with potential antineoplastic activity. Chidamide selectively binds to and inhibits HDAC leading to an increase of acetylation levels of histone protein H3. This agent also inhibits the expression of signaling kinases in the PI3K/Akt and MAPK/Ras signaling pathways and may result in cell cycle arrest and the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells. |
| 保存条件: | -20℃ |
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