UK-371804 HCl  ≥98% (HPLC)

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包装规格:5mg 25mg 100mg in glass bottle
溶解性:溶于DMSO(10 mg/mL 加热)
产品描述:一种可逆的、高效的尿激酶型纤溶酶原激活剂(uPA)的抑制剂,Ki:10 nM。UK-371,804 is a reversible, substrate-competitive, highly potent (Ki = 10 nM) and selective urokinase-type plasminogen activator (uPA) Inhibitor with excellent selectivity over tPA, plasmin, Factor IXa and Xa. When applied topically, UK-371,80 effectively penetrates into excisional wounds of experimental pigs with no adverse effect on wound closure. UK-371,804 effectively blocks EGR-FMK from binding human uPA even in the presence of tissue proteins.
保存条件:-20℃