生物试剂
>
生化试剂
>
分析化学
> 曲克芦丁 促销
加入收藏 取消收藏

曲克芦丁 促销  98.248%(HPLC-ELSD),分析标准品

促销价¥{{model.attbuying.price}}

市场价¥0.00

累计销量0 累计评价0 人评论

别称 {{model.alias}}
中文名称 {{model.name}}
英文名称 {{model.enname}}
品牌 {{model.brand}}
CAS {{model.cas}}
分子式
分子量 {{model.molecularweight}}
MDL {{model.mdl}}
货号 {{model.procode}}
数量

+ -

件 库存{{model.attbuying.number}}件
立即购买 加入购物车 下载说明书

看了又看
包装规格：20mg in glass bottle
产品描述：基本信息 产品编号： T10193 产品名称： Trihydroxyethylrutin CAS: 7085-55-4   储存条件 粉末 2-8℃ 四年     分子式： C33H42O19 溶于液体 -80℃ 两年 分子量 742.70 -20℃ 一个月 化学名：  3,5-Dihydroxy-3',4',7-tris(2-hydroxyethoxy)flavone 3-rutinoside Solubility (25°C)：   体外:   DMSO 100mg/mL (134.64mM) Ethanol Insoluble Water 100mg/mL warmed with 50ºC water bath (134.64mM) 体内(现配现用): 1.请依序添加每种溶剂：0.5% CMC-Na/saline water Solubility: 24mg/mL (32.32mM); Clear solution; Need ultrasonic 2.请依序添加每种溶剂：10% DMSO→40% PEG300→5% Tween-80→45% saline Solubility: ≥ 2.5mg/mL (3.37mM); Clear solution 此⽅案可获得 ≥ 2.5mg/mL (3.37mM，饱和度未知) 的澄清溶液。 以 1mL ⼯作液为例，取 100μL 25.0mg/mL 的澄清 DMSO 储备液加到 400μL PEG300 中，混合均匀；向上述体系中加⼊ 50μL Tween-80，混合均匀；然后继续加⼊ 450μL ⽣理盐⽔定容⾄ 1mL。 3.请依序添加每种溶剂：10% DMSO→90% (20% SBE-β-CD in saline) Solubility: ≥ 2.5mg/mL (3.37mM); Clear solution 此⽅案可获得 ≥ 2.5mg/mL (3.37mM，饱和度未知) 的澄清溶液。 以 1mL ⼯作液为例，取 100μL 25.0mg/mL 的澄清 DMSO 储备液加到 900μL 20% 的 SBE-β-CD ⽣理盐⽔⽔溶液中，混合均匀。 4.请依序添加每种溶剂：10% DMSO→90% corn oil Solubility: ≥ 2.5mg/mL (3.37mM); Clear solution 此⽅案可获得 ≥ 2.5mg/mL (3.37mM，饱和度未知) 的澄清溶液，此⽅案不适⽤于实验周期在半个⽉以上的实验。 以 1mL ⼯作液为例，取 100μL 25.0mg/mL 的澄清 DMSO 储备液加到 900μL ⽟⽶油中，混合均匀。 ＜1mg/ml表示微溶或不溶。 普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。   制备储备液   浓度   溶液体积 质量   1mg   5mg   10mg 1mM 1.3465mL 6.7324mL 13.4647mL 5mM 0.2693mL 1.3465mL 2.6929mL 10mM 0.1346mL 0.6732mL 1.3465mL 50mM 0.0269mL 0.1346mL 0.2693mL   生物活性 产品描述 Troxerutin 是一种黄酮醇类，是一种黄酮类化合物。 靶点   体外研究 Troxerutin (Trihydroxyethylrutin)，从槐花中分离的一种天然生物类黄酮，被报道具有许多益处和药用价值。Troxerutin降低同型半胱氨酸，α-氨基己二酸，胆固醇，甘油三酯，以及低密度脂蛋白载脂蛋白B在急性心肌梗塞患者血浆中的水平。Troxerutin减少红细胞聚集，并对郁积，毛细血管灌注和慢性静脉功能不全的营养并发症具有积极作用。Troxerutin通过减少糖基化终产物，活性氧和蛋白羰基水平，并且增强磷脂酰肌醇3-激酶/Akt的激活减弱D-半乳糖诱导的认知损害和氧化应激。   推荐实验方法(仅供参考) Cell Assay The cells are plated at a density of 4×103 /well in a 96-well plate. At 70 to 80% confluence, the cells are treated with Troxerutin at concentrations ranging between 0 and 60μM for 24 h at 37°C. Subsequently, 10μL water soluble tetrazolium salt assay solution is added to each well and, following incubation for 30 min at 37°C, the optical density is measured at 490 nm using a reader. To examine Troxerutin mediated ROS protection, the cells are pretreated with Troxerutin at the following concentrations: 0, 5, 10 and 15μM for 8 h. Subsequently, 750μM H2O2 is added to each well. Following incubation for 24 h at 37°C, cell viability is evaluated using an Cell Viability Assay kit. The level of cell viability (%) is normalized to that of 0.1% dimethyl-sulfoxide (DMSO)-treated cells. Each experiment is repeated at least three times     Animal Administration Thirty two adult male Wistar rats weighing 250 to 300 grams are used in this study. The animals are randomly divided into four groups (n=8/each) as: group I: control (C), group II: control with Troxerutin (C+TXR), group III: diabetic (D), and group IV: diabetic with Troxerutin (D+TXR). The control rats are received the same amount of citrate buffer alone. Development of diabetes is confirmed by measuring blood glucose levels, 72 hours later. Animals with blood glucose levels higher than 16.65mM (300mg/dL) are considered diabetic and those with blood glucose levels lower than this value are excluded from the experiment. Troxerutin (150mg/kg/day) is administered orally, once daily for four weeks. After 10 weeks of induction of diabetes, diabetic animals as well as the time-matched controls are killed and aortic samples are collected
保存条件：2-8℃

猜你喜欢