MLS000532223 ≥98%
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| 包装规格: | 2mg 5mg 10mg 25mg 50mg 100mg in glass bottle |
| 产品简介: | MLS000532223 是一种选择性的,具有高亲和力的 Rho 家族 GTPases (Rho family GTPases) 抑制剂,其 EC50 值的范围为 16-120 μM。MLS000532223 能阻止 GTP 与几种 GTPases 相结合。 |
| 溶解性: | DMSO : 50 mg/mL (199.01 mM; Need ultrasonic) |
| 储备液保存: | -80°C, 2 years -20°C, 1 year |
| 靶点: | EC50: 16-120 μM (Rho family GTPases) |
| 体外研究: | MLS000532223 prevents GTP binding to several GTPases in a dose-dependent manner. MLS000532223 modulates Rho-family GTP-binding kinetics. MLS000532223 is active in cell-based assays and inhibits EGF-stimulated Rac 1 activation. MLS000532223 inhibits actin rearrangements and changes in cell morphology that are downstream of Rho family GTPase activation. MLS000532223 (10 μM) modulates actin remodeling in mast cells. MLS000532223 (10 μM) inhibits ligand-stimulated β-hexosaminidase secretion of RBL cells. |
| 保存条件: | -20°C |
| 注意事项: | 1、为了您的安全和健康,请穿实验服并戴一次性手套操作。 2、以上信息仅做参考交流之用。 |
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