Litronesib  ≥98%

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包装规格:5mg 10mg 25mg 50mg 100mg in glass bottle
溶解性:溶于DMSO(≥50mg/mL)
产品描述:一种选择性的有丝分裂特异性运动蛋白 Eg5 抑制剂,具有抗肿瘤的活性。Litronesib, also known as LY2523355, is a n inhibitor of the kinesin-related motor protein Eg5 with potential antineoplastic activity. Litronesib selectively inhibits the activity of Eg5, which may result in mitotic disruption, apoptosis and consequently cell death in tumor cells that are actively dividing. The ATP-dependent Eg5 kinesin-related motor protein (also known as KIF11 or kinesin spindle protein-5) is a plus-end directed kinesin motor protein that plays an essential role during mitosis, particularly in the regulation of spindle dynamics, including assembly and maintenance. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
保存条件:-20℃