Dofequidar  

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包装规格:100mg in glass bottle
产品描述:一种新型的喹啉化合物,能逆转P-糖蛋白(P-gp)介导的多药抗性。Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.
保存条件:-20℃