TMS  ≥98%

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包装规格:100mg 250mg 1g in glass bottle
溶解性:溶于DMSO(≥50mg/ml)
产品描述:一种选择性和竞争性CYP1B1抑制剂,IC50为6nM,Ki值为3nM。TMS对CYP1A1(IC50=300nM)和CYP1A2(IC50=3.1μM)的抑制作用较小。TMS是白藜芦醇的甲基化衍生物,具有抗癌活性。TMS, also knonw as Tetramethoxystilbene, is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. TMS is also a resveratrol analogue, which suppressed induced differentiation of C3H10T1/2 cells. TMS can suppress adipogenic differentiation of C3H10T1/2 cells by inhibiting PPARγ. 2,3',4,5'-Tetramethoxystilbene prevents deoxycorticosterone-salt-induced hypertension: contribution of cytochrome P-450 1B1.
保存条件:-20℃