β3-AR agonist 2  

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包装规格:25mg 50mg 100mg in glass bottle
产品简介:一种有效的选择性β3肾上腺素能受体(β3-adrenergic receptor,β3-AR)激动剂,EC50为8nM。
靶点:EC50: 8 nM (β3-adrenergic receptor)
体外研究:β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 receptor.
体内研究:β3-AR agonist 2 (Compound 26e) has significant thermogenesis effects on human β3-adrenergic receptor transgenic mice. β3-AR agonist 2 acts as a potential drug for the treatment of human obesity and type II diabetes.
保存条件:-20℃
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