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胍法辛  

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包装规格：10mg 25mg 50mg 100mg in glass bottle
产品简介：一种α2A肾上腺素受体激动剂，Kd为31 nM，具有抗高血压的活性。 Guanfacine is a centrally acting antihypertensive agent with specificity to wards adrenergic alpha-2 receptors.
体外研究：Guanfacine increases the delay-related neuronal firing needed for working memory on dIPFC neurons at the cellular level. Guanfacine improves PFC cognitive function by inhibiting the production of CAMP, closing HCN channels, and strengthening the PFC networks.
体内研究：Guanfacine enhances PFC working memory function in aged monkeys and improves impulse control in monkeys performing a delayed discounting task. Guanfacine improves cognitive performance when infused directly into the rat or monkey PFC. Guanfacine blocks 2A receptors in the monkey dIPFC markedly impairs working memory, behavioral inhibition and greatly reduces persistent neuronal firing.
保存条件：-20℃
注意事项：1、为了您的安全和健康，请穿实验服并戴一次性手套操作。 2、以上信息仅做参考交流之用。

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