二氯美维库铵  ≥98%

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包装规格:25mg 100mg in glass bottle
产品简介:一种苄基异喹啉衍生物,也是一种短效非去极化神经肌肉阻滞剂和骨骼肌松弛剂。Mivacurium dichloride可与nAChR偶联,以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。
溶解性:溶于DMSO(250mg/ml 超声)
储备液保存:-80°C, 6 months -20°C, 1 month (stored under nitrogen, away from moisture)
体外研究:Mivacurium induces LAD2 cell degranulation in a dose-dependent manner. Mivacurium stimulates intracellular Ca2+ influx in MRGPRX2-HEK293 cells but not in NC-HEK293 cells. Mivacurium induces the release of only low levels of mediators in LAD2 cells transfected with MRGPRX2-targeted small interfering siRNA.
体内研究:Mivacurium causes pseudo-allergic reactions in C57 wild-type mice by inducing mast cells to release histamine and a decrease in body temperature. Mivacurium is rapidly hydrolyzed in the plasma and has a short duration of action (< 10 min). Mivacurium has many advantages, such as a rapid effect, nonneurological toxicity and a lack of heart rate alteration.
保存条件:-20℃
注意事项:1、为了您的安全和健康,请穿实验服并戴一次性手套操作。 2、以上信息仅做参考交流之用。