8-Azido-ATP  

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包装规格:1mg in glass bottle
产品简介:一个光解性的核苷酸类似物,用于鉴定蛋白,如依赖于DNA的RNA聚合酶。
体外研究:8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light. 8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner. 8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP.
保存条件:-20℃
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