Mps1-IN-3  ≥98%

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包装规格:1mg 5mg 10mg 25mg 50mg 100mg in glass bottle
产品描述:一种有效的,选择性的 MPS1 抑制剂,IC50 值为 50 nM。MPS1-IN-3 is a selective and potent MPS1 inhibitor with phenotypic consequences similar to those reported for published MPS1 inhibitors such as MPS1-IN-1, MPS1-IN-2, and AZD3146. MPS1-IN-3 sensitizes glioblastoma cells to vincristine both in vitro and in murine tumor models. MPS1 may be a promising therapeutic target for high-grade glioma therapy and that MPS1 inhibition by MPS1-IN-3 efficiently sensitizes glioblastoma cells to antimitotic agents.
保存条件:-20℃