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Coenzyme FO  ≥98%

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溶解性：溶于DMSO（5 mg/mL 超声)
产品描述：基本信息 产品编号：C10734 产品名称：Coenzyme FO CAS: 37333-48-5   储存条件 粉末 -20℃ 四年     分子式： C16H17N3O7 溶于液体 -80℃ 两年 分子量 363.32 -20℃ 一个月 化学名：  1-Deoxy-1-(2,4-dihydroxy-8-oxopyrimido[4,5-b]quinolin-10(8H)-yl)pentitol   Solubility (25°C)   体外 DMSO 5mg/mL (13.76mM Need ultrasonic) Ethanol   Water   体内 现配现用   ＜1mg/ml表示微溶或不溶。 普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。     制备储备液   浓度   溶液体积 质量   1mg   5mg   10mg 1mM 2.7524mL 13.7620mL 27.5239mL 5mM 0.5505mL 2.7524mL 5.5048mL 10mM 0.2752mL 1.3762mL 2.7524mL     生物活性 产品描述 一种脱氮黄素发色团，在产甲烷途径中起着重要的氢化物受体/供体作用。 靶点/IC50 Bacterial Endogenous Metabolite   体外研究 The formation of Coenzyme FO is mediated by two separate radical SAM active sites, one each in the CofG and CofH enzymes or both in the FbiC enzyme. These two radical SAM domains constitute the functional domains of Fo synthase. F420 is biosynthesized in Methanocaldococcus jannaschii by the action of eight enzymes with the formation of the deazaflavin chromophore (Fo) as the remaining unsolved step.Coenzyme F420 is the central low-redox-potential electron carrier in methanogenic metabolism. Coenzyme F420 is reduced under hydrogen by the action of F420-dependent hydrogenase.Coenzyme F420 acts as a hydride transfer coenzyme for an F420-specific glucose-6-phosphate dehydrogenase (Fgd) in mycobacteria. Coenzyme F420 is found in all methanogenic and certain nonmethanogenic archaea, where it participates in energy metabolism, NADP reduction, oxygen detoxification, and sulfite reduction. By converting NO2 back to NO with F420H2, M. tuberculosis could decrease the effectiveness of antibacterial action of macrophages.
保存条件：-20℃

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