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Sufugolix  ≥98%(HPLC)

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包装规格：5mg 25mg 50mg 100mg in glass bottle
溶解性：溶于DMSO(1mg/mL 超声 加热)
产品描述：一种口服有效的LHRH(黄体激素释放激素)受体拮抗剂，IC50值为0.1nM。Sufugolix is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively). It was under development for the treatment of endometriosis and uterine leiomyoma and reached phase II clinical trials for both of these indications, but was subsequently discontinued. It seems to have been supplanted by relugolix (TAK-385), which is also under development by Takeda for the treatment of these conditions and has a more favorable drug profile (including reduced cytochrome P450 inhibition and improved in vivo GnRHR antagonistic activity) in comparison.
保存条件：-20℃

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