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氟哌啶醇盐酸盐  

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包装规格：100mg 500mg in glass bottle
产品描述：基本信息 产品编号： H10404  产品名称： Haloperidol hydrochloride CAS: 1511-16-6   储存条件 粉末 -20℃ 四年 分子式： C21H24Cl2FNO2 溶于液体 -80℃ 二年 分子量： 412.33     化学名：  1-Butanone,4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-,hydrochloride (1:1) Solubility (25°C)：   体外:   DMSO   Ethanol   Water   体内(现配现用):   ＜1mg/ml表示微溶或不溶。 普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。   生物活性 产品描述 一种有效的 dopamine D2 receptor 拮抗剂。 靶点 Dopamine Receptor 体内研究 Haloperidol (1mg) intra-arterially attenuates the dopamine-induced pancreatic secretion.Haloperidol (3mg) completely inhibits the action of 10μg of dopamine in the pancreas of the dogs.Haloperidol (10mg/kg) as well as chlorpromazine (CPZ,15mg/kg) blocks mescaline-induced altered behavior within 7 to 10 minutes when injected into the mice 45 minutes after 50mg/kg (2µc) of mescaline. Haloperidol has no effect on mescaline disappearance.   推荐实验方法(仅供参考) 动物实验:   Male albino mice of Swiss-Webster strain (33-36g) are used,and all substances are given by i.p.injection in a volume of 0.5mL.CPZ,haloperidoi and mescaline are all in time form of timeir imydrochlorides and the dose solutions are prepared at concentrations of 1.0,0.66 and 3.3mg/mL of 0.9% saline,respectively.The doses are:CPZ,15mg/kg;haloperidol,10mg/kg;mescaline,50mg/kg.Mice are pretreated with either CPZ or haloperidol 30 minutes before administration of mescaline.In some instances CPZ is injected 45 minutes after mescaline.Time animals are hmoused individually in a plexiglas cage and the gross behavior and locomotor activity.At selected intervals after mescaline,groups of mice are sacrificed by decapitation.Plasma is separated and stored at -20℃. The brain,liver,kidney,lung,spleen and heart are frozen on dry ice and stored at -20℃ for 18 to 20 hours before they are used for assays.
保存条件：-20℃

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