BAY1082439  ≥98%(HPLC)

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包装规格:5mg 25mg 100mg in glass bottle
溶解性:溶于DMSO。
产品描述:一种具有潜在抗肿瘤活性的PI3Kα/β抑制剂。BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha and beta isoforms with potential antineoplastic activity. PI3K alpha/beta inhibitor BAY1082439 selectively inhibits both PI3K alpha, including mutated forms of PIK3CA, and PI3K beta in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K-expressing and/or PTEN-driven tumor cells. By specifically targeting class I PI3K alpha and beta, this agent may be more efficacious and less toxic than pan PI3K inhibitors.
保存条件:-20℃