BAY1082439 ≥98%(HPLC)
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| 包装规格: | 5mg 25mg 100mg in glass bottle |
| 溶解性: | 溶于DMSO。 |
| 产品描述: | 一种具有潜在抗肿瘤活性的PI3Kα/β抑制剂。BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha and beta isoforms with potential antineoplastic activity. PI3K alpha/beta inhibitor BAY1082439 selectively inhibits both PI3K alpha, including mutated forms of PIK3CA, and PI3K beta in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K-expressing and/or PTEN-driven tumor cells. By specifically targeting class I PI3K alpha and beta, this agent may be more efficacious and less toxic than pan PI3K inhibitors. |
| 保存条件: | -20℃ |
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