U-104(NSC 213841)  ≥98%(HPLC)

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包装规格:5mg 10mg 25mg 50mg 100mg in glass bottle
产品简介:一种CAⅨ抑制剂,Ki:45.1nM。 U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX。
溶解性:溶于DMSO(>15mg/mL)
产品描述:一种CAⅨ抑制剂,Ki:45.1nM。 U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX。
保存条件:-20℃